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Compare adequate intraoperative fluid therapy with Ondansetron on the incidence and severity of nausea and vomiting after general surgery

Compare adequate intraoperative fluid therapy with Ondansetron on the incidence and severity of nausea and vomiting

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016080219359N6
Enrollment
120
Registered
2016-09-03
Start date
2016-04-03
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia. Symptoms and signs involving the digestive system and abdomen

Interventions

Intervention 1: The first Group: Under the prophylactic treatment liquid. Intervention 2: The second Group: pharmacological intervention with ondansetron 0.06 mg per kg of patient weight. Intervention
Treatment - Drugs
The second Group: pharmacological intervention with ondansetron 0.06 mg per kg of patient weight

Sponsors

Vice Chancellor for Research, North Khorasan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients should be alert; having class 1 and class 2 of America Society of Anesthesiology (ASA) score Exclusion criteria: the patients who weigh more than 90 kg; diabetics; with underlying gastrointestinal disease; those who had used anti-nausea and anti-vomiting drugs in pre-operative 24 hours before the surgery; those who were not fasting; those with middle ear disease; those who had more than 20% of baseline drop in blood pressure after spinal anesthesia; history of nausea and vomiting during the past 24 hours

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Severity of nausea. Timepoint: During the surgery, 2 hour after the surgery, 6 hour after the surgery. Method of measurement: self-report scale.;Severity of vomiting. Timepoint: During the surgery, 2 hour after the surgery, 6 hour after the surgery. Method of measurement: self-report scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Shahinfar

North Khorasan University of Medical Sciences

dr.jshahinfar@gmail.com+98 58 3229 6966

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026