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Efficacy of Levetiracetam In pedatrics migrain headache

Comparison of the levetiracetam, sodium valproate and propranolol effect in preventing migraine headaches in children with migraine

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160802029171N3
Enrollment
39
Registered
2018-02-18
Start date
2018-02-20
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine. G43

Interventions

Intervention 1: Intervention group: Will be treated with oral levetiracetam tablet ((S)-2-(2-Oxopyrrolidin-1-yl)butanamide), the product of Cobel Darou company, at a dose of 20 mg/kg of body weight o

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 15 Years

Inclusion criteria

Inclusion criteria: Migraine headache according to ICHD-3 criteria The patient's age of 5-15 years Written consent from the patient or his parents/guardians Normal radiological and neurological findings

Exclusion criteria

Exclusion criteria: Recent history of head trauma Drug abuse Having a secondary headache due to infection(Otitis media or sinusitis,..)

Design outcomes

Primary

MeasureTime frame
Headache Severity: indicates the pain caused by the headache. Grade 0 means no pain, Grade 1 means mild pain, Grade 2 means moderate pain and Grade 3 means severe pain. Timepoint: 1 month. Method of measurement: Headache severity is measured based on headache score.;Headache frequency: indicates repetition of headache attacks per 24 hours, week or month. Timepoint: 1 month. Method of measurement: headache frequency will be measured with asking question from patient and his parents.;Headache disability: indicates the number of days that a person can not perform his or her daily tasks due to a headache. Timepoint: 1 month. Method of measurement: Headache disability will be measured with based on pediatric migraine disability assessment.

Secondary

MeasureTime frame
Sleepiness: a feeling of being sleepy and lethargic. Timepoint: 1 month. Method of measurement: Sleepiness will be measured by asking question from childs and/or their parents.;Agitation: a state of anxiety or nervous excitement. Timepoint: 1 month. Method of measurement: Agitation will be measured by asking question from childs and/or their parents and clinical experiments.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Afshin Fayyazi

Hamedan University of Medical Sciences

Afshin_fay@yahoo.com+81 38381491

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026