Fractures in lower limbs. Fractures involving multiple regions of both lower limbs
Conditions
Interventions
Intervention 1: Intervention group 1: Patients in this group received 20 mg morphine by PCA pump and placebo tablets (similar to buprenorphine pills). Intervention 2: Intervention group 2: Patients in
Prevention
Intervention group 1: Patients in this group received 20 mg morphine by PCA pump and placebo tablets (similar to buprenorphine pills).
Intervention group 2: Patients in this group received buprenorphine tablets and placebo PCA pump (normal saline).
Sponsors
Ardabil University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Lower Limb Orthopedic Surgery ASA class I or II age between 20 and 60 years old
Exclusion criteria
Exclusion criteria: Previous hypersensitivity to Buprenorphine Previous hypersensitivity to Morphine History of analgesic use in the past 24 hours Pregnant and lactating women Addiction to Narcotic or Alcohol or Benzodiazepines
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain. Timepoint: at 1, 8, 16, and 24 hours after surgery. Method of measurement: Visual Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea. Timepoint: at 1, 8, 16, and 24 hours after surgery. Method of measurement: N/V Score.;Vomiting. Timepoint: at 1, 8, 16, and 24 hours after surgery. Method of measurement: N/V Score.;Itching. Timepoint: at 1, 8, 16, and 24 hours after surgery. Method of measurement: asking the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaba Esmaeeli
Ardabil University of Medical Sciences
Outcome results
None listed