melasma. Chloasma
Conditions
Interventions
Intervention 1: Intervention group 1: Cases will be treated with Methimazole 5% topical cream once a night for 8 weeks. Intervention 2: Intervenion group 2: The control group will be treated with Hydr
Treatment - Drugs
Intervention group 1: Cases will be treated with Methimazole 5% topical cream once a night for 8 weeks.
Intervenion group 2: The control group will be treated with Hydroquinone topical cream 2% once a night for 8 weeks.
Sponsors
Vice chancellor for research, Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Days to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Ages from 18 to 50; Normal to dry skin; without comedones Exclusion criteria: Absence of follow up by patients and not satisfied to continue; Complications such as allergy to topical agent; Pregnancy and lactation; Thyroid disease; Oral contraceptive pills use and other drugs that cause melasma.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hyperpigmentation of face skin. Timepoint: At first and 8 weeks after treatment. Method of measurement: Intensity of the darkening of the face skin compared to other areas of the face with visioface device. | — |
Secondary
| Measure | Time frame |
|---|---|
| Satisfaction amount. Timepoint: After completion of treatment. Method of measurement: Comparison of reduction hyperpigmentation by patient, before and after treatment According to schedule. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSedighe Naeji
Iran University Of Medical Sciences
Outcome results
None listed