post spinal shivering. Complication of anaesthesia during labour and delivery, unspecified
Conditions
Interventions
Intervention 1: After spinal anesthesia, in group A 2mg/kg hydrocortison (3ml),after clamping of umblical cord intravenously is injected. Intervention 2: After spinal anesthesia , in ketamine group ,0
Prevention
Placebo
After spinal anesthesia, in group A 2mg/kg hydrocortison (3ml),after clamping of umblical cord intravenously is injected.
After spinal anesthesia , in ketamine group ,0.5 mg/kg ketamine (3ml) after clamping of umblical cord intravenously is injected .
After spinal anesthesia, in control group 3ml normal salin , after clamping of umblical cord intravenously is injected.
Sponsors
Hamadan University of Medical Sciences, vice chancellor for research
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: pregnant women aged 18 -40 years old; ASA class 1&2; term pregnant patients (gestational age 36-40 weeks) and candidate for cesarean section under spinal anesthesia . Exclusion criteria: high risk pregnancy; multiple pregnancy; emergency cesarean section; pre-eclampsia & eclampsia; cardiovascular disease; respiratory disease; psychiatric disease; thyroid disease; diabetes melitus; long history of corticosteroids administration; hypertension; peptic ulcer; need to get blood products; temperature >38 c and contraindication of spinal anesthesia.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic and diastolic blood presure. Timepoint: 1-2-3-4-5-10-15-20-30-40-50-60 minutes after spinal anesthesia and 10-20 &30 minutes after arriving to recovery. Method of measurement: mmHg and by noninvasive automatic blood pressure monitoring.;Mean arterial pressure. Timepoint: 1-2-3-4-5-10-15-20-30-40-50-60 minutes after spinal anesthesia and 10-20 &30 minutes after arriving to recovery. Method of measurement: mmHg and by noninvasive automatic blood pressure monitoring.;Heart Rate. Timepoint: 1-2-3-4-5-10-15-20-30-40-50-60 minutes after spinal anesthesia and 10-20 &30 minutes after arriving to recovery. Method of measurement: Beat per minute and by ECG monitoring.;SPO2. Timepoint: 1-2-3-4-5-10-15-20-30-40-50-60 minutes after spinal anesthesia and 10-20 &30 minutes after arriving to recovery. Method of measurement: Percent and by pulse oxymetry.;Tempreture. Timepoint: each 15 minutes until end of recovery. Method of measurement: degree and by medical oral termometer.;Frequency of shivering. Timepoint: during sergury and in recovery. Method of measurement: Observation.;Shiverig grading. Timepoint: during sergury and in recovery. Method of measurement: shivering score.;Consumption of pethidine. Timepoint: during sergury and in recovery. Method of measurement: mg and by observation.;Consumption ofephedrine. Timepoint: during sergury and in recovery. Method of measurement: mg and by observation.;Neonate APGAR. Timepoint: 1&5 minutes after birth. Method of measurement: APGAR Score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation score. Timepoint: 1-2-3-4-5-10-15-20-30-40-50-60 minutes after spinal anesthesia and 10-20 &30 minutes after arriving to recovery. Method of measurement: Ramsay score.;Hallocination. Timepoint: during surgery & recovery. Method of measurement: observation & interview.;Nausea & vomiting. Timepoint: during surgery. Method of measurement: observation & interview.;Nistagmus. Timepoint: during surgery & recovery. Method of measurement: Observation & Examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNahid Manouchehrian
Hamadan University of Medical Sciences, Fatemie Hospital
Outcome results
None listed