Effect of transcranial Direct Current Stimulation (tDCS) in cigarette smokers treatment.

Comparison of the trans-cranial Direct Current Stimulation (tDCS) and Bupropion on treatment of nicotine-dependent smokers.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016072629093N1

Enrollment

175

Registered

2016-12-25

Start date

2016-11-22

Completion date

Unknown

Last updated

2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nicotine dependence in cigarette smokers. Nicotine dependence, cigarettes

Interventions

Intervention 1: Nicotine Replacement Therapy with 300 mg Bupropione tablet, daily, for 8 weeks. Intervention 2: Active stimulation (transcranial Direct Current Stimulation with 2 mA amplitudes for 20

Eligibility

Sex/Gender

Male

Age

15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Right-handed, 15 to 65 years old smokers who are nicotine addicted according to DSM-5

Exclusion criteria

Exclusion criteria: Other substances use (heroin, amphetamines, cannabis) psychiatric diseases (Depression, Bipolar Mood Disorders, ...) physical disease (brain tumors, seizure attacks, ...) drug use containing calcium, sodium, potassium Other tobacco use, such as chops and hookahs

Design outcomes

Primary

Measure	Time frame
Salivary Cotinine. Timepoint: before intervention, end of intervention, after 6 months. Method of measurement: Salivary Cotinine ELISA Kit - Salimetrics.;Fagerstrom Test for Nicotine Dependence. Timepoint: before intervention,weekly during intervention,monthly until 6 months follow up. Method of measurement: Fagerstrom Questionnaire Completion - Self Declaration.	—

Secondary

Measure	Time frame
Craving. Timepoint: Befor intervention, weekly during intervention,end of the 6 months follow up. Method of measurement: Tobacco craving questionnaire-short form.;Powerity of brain wave in Quantitative electroencephalogram. Timepoint: Befor intervention, weekly during intervention,end of 6 month follow up. Method of measurement: Quantitative electroencephalogram.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahram Ghorbani Behnam

Shahroud University of Medical Sciences

ghorbani@shmu.ac.ir+98 23 3239 5003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026