Sickle cell anemia. Sickle-cell anaemia with crisis
Conditions
Interventions
Intervention 1: Intervention group I: Patients with sickle cell anemia are receiving 30 mg injection ketorolac. Pain reliefs will assessment based on the visual analog scale before and 5 minutes after
Treatment - Drugs
Intervention group I: Patients with sickle cell anemia are receiving 30 mg injection ketorolac. Pain reliefs will assessment based on the visual analog scale before and 5 minutes after intervention.
Intervention group II: Patients with sickle cell anemia are receiving 4-10 mg injection morphine at 4 to 5 ml injection water solution. Pain reliefs will assessment based on the visual analog scale be
Sponsors
Vice Chancellor for Research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: use of studying medicine; no prior history of cardiovascular and respiratory diseases; not having hypertension; not using other analgesic drug. Exclusion criteria: unwillingness to continue the study; major side-effects due to the use of medications; addicted, especially for morphine injection; having sensitivity.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain relief. Timepoint: Before and 5 minutes after intervention. Method of measurement: The visual analog scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side-effects of medications (nausea and vomiting, dizziness, respiratory depression, skin rash in the area of injection, menorrhagia after injection, hypotension, seizures, drowsiness, allergic reactions, etc). Timepoint: 5 minutes after intervention. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSomaye Sadat Hosseiny
Mashhad University of Medical Sciences
Outcome results
None listed