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Comparison of efficacy Dapsone 5% with Erythromycin 2% in treatment of mild papulopustular acne

Comparison of efficacy Dapsone 5% with Erythromycin 2% in treatment of mild papulopustular acne

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201607232581N5
Enrollment
50
Registered
2016-11-22
Start date
2016-11-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild papulopustular acne. Acne vulgaris

Interventions

Intervention 1: Interventional group
treatment with five percent dapsone gel, twice a day for a month. Intervention 2: Control group
treatment with twe percent erythromycin gel, twice a day for a month.
Treatment - Drugs
treatment with five percent dapsone gel, twice a day for a month
Control group
treatment with twe percent erythromycin gel, twice a day for a month

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with Papulopustular mild acne; age greater than 12 years old; normal levels of G6PD Exclusion criteria: patient's decision to exit the study; the risk of severe and moderate conglobata acne or nodulocystic acne; use of topical medications in the past week; taking oral medications in the past four weeks; have allergy to dapsone sulfate; pregnancy or planning to pregnancy or breastfeeding; lesions have been exacerbated enough that the need for systemic therapy; use of isotretinoin in 3 months ago; patients under 12 years of age old; G6PD deficiency

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Acne severity index. Timepoint: zero,second,forth weeks and third month. Method of measurement: Counting.

Secondary

MeasureTime frame
Number of papule. Timepoint: zero,second,forth weeks and third month. Method of measurement: count.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHarizchi ghadim Hamide

Tabriz University of Medical Sciences

drherizchi@yahoo.com+98 41 3541 2101

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026