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Effects of Myo-inositol in poor responder patients undergoing intracytoplasmic sperm injection

Effects of Myo-inositol on IVF outcomes in poor responders undergoing intracytoplasmic sperm injection and comprission with folic acid:a randomised clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160722029027N8
Enrollment
148
Registered
2019-07-27
Start date
2016-04-20
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Noninflammatory disorders of female genital tract. Complication associated with artificial fertilization, unspecified

Interventions

Intervention 1: Intervention group: Myoinositol 4 gr and Folic Acid 400 microgram was administered one month before the cycle and ovarian stimulation with antagonist protocol will be started on day 2

Sponsors

Vice Chancellor for research of Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
No minimum to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age below 45 years Body mass index (BMI) between 20-30 low ovarian reserve [both ovarian AFC below 7 or AMH below 1.1 ng/ml or low ovarian response in previous cycle (below 3 oocyte) none history of allergy to Myo-inositol

Exclusion criteria

Exclusion criteria: unwillingness to continue

Design outcomes

Primary

MeasureTime frame
Number of metaphase II oocyte. Timepoint: Time of oocyte pick up. Method of measurement: According to embryolog criteria.;Chemical pregnancy. Timepoint: 2 weeks after embryo transfer. Method of measurement: Serum ßHcG test.

Secondary

MeasureTime frame
Clinical pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: Transvaginal ultrasound.;Ongoing pregnancy. Timepoint: 10 weeks after embryo transfer. Method of measurement: Vision fetal heart beat in ultrasound.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila Nazari

Shahid Beheshti University of Medical Sciences

nazari@sbmu.ac.ir+98 21 2243 2558

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026