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Studying the effectiveness of vaginal radiofrequency on embryo implantation in pregnant women with recurrent implantation failure

Comparison of the effect of endometrial platelet-rich plasma injection with and without vaginal radiofrequency on pregnancy rates in patients with recurrent implantation failure

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160722029027N17
Enrollment
60
Registered
2025-09-08
Start date
2025-10-05
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Repeated implantation failure. Female infertility of uterine origin

Interventions

Intervention 1: Intervention group: Includes patients with recurrent implantation failure and infertility with inclusion criteria referred to Nikan Hospital in Tehran who are treated with platelet-ric

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 43 Years

Inclusion criteria

Inclusion criteria: Women under 44 years of age A history of at least 2 failed transfers Not founding an underlying cause, such as thrombophilia with a genetic disorder for IVF failure Having at least 3 frozen embryos with grades A and B

Exclusion criteria

Exclusion criteria: Pacemaker or any metal device in the pelvic area.

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy. Timepoint: Presence of gestational sac with fetal heart activity on ultrasound at 7 weeks of pregnancy. Method of measurement: Sonography (visualization of the fetal heart).

Secondary

MeasureTime frame
Chemical pregnancy (HCGß). Timepoint: Increased serum ß-hCG levels of more than 10 mIU/mL within two weeks after embryo transfer. Method of measurement: Laboratory kit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Samira Yavari

Shahid Beheshti University of Medical Sciences

s.yavari@sbmu.ac.ir+98 912 765 5905

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026