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Comparison of the effect of intraovarian injection of PRGF and PRP on improving the response and pregnancy outcomes

Comparison of the effect of intraovarian injection of Plasma Rich Growth Factor (PRGF) and Plasma Rich Platelate (PRP) on improving the response and pregnancy outcomes in women undergoing IVF with poor ovarian response

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160722029027N12
Enrollment
30
Registered
2022-05-14
Start date
2022-05-10
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patient with diminished ovarian reserve.

Interventions

Intervention 1: In the intervention group, 1:35 cc of blood is taken from women. The blood sample is centrifuged at 1200 rpm for 12 minutes to separate the red blood cells. The extracted plasma is cen

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
No minimum to 42 Years

Inclusion criteria

Inclusion criteria: Women under the age of 42 Having a history of low ovarian reserve (less than 3 eggs in the previous IVF cycle) Abnormal laboratory tests anti mulerian hormone fewer than 1.1ng /dl Counting antral follicles 5-7 on transvaginal sonography

Exclusion criteria

Exclusion criteria: Women with anemia diagnosis history of malignancy Any endocrine disorders (hypothyroidism, hyperprolactinemia)

Design outcomes

Primary

MeasureTime frame
The rate of clinical pregnancy in the two groups undergoing PRGF and the PRP. Timepoint: 4 week after embryo transfer. Method of measurement: By seeing the fetal heartbeat on ultrasound.

Secondary

MeasureTime frame
The number of retrieved oocytes in the two groups injected with PRGF and PRP. Timepoint: During ovarian puncture. Method of measurement: counting.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Razghandi

Shahid Beheshti University of Medical Sciences

z.razghandi@gmail.com+98 21 2243 2560

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026