The effect of dill vaginal cream on treatment of candida vaginitis

The comparision effect of Anethum graveolens L. (dill) products on traditional medicine base with clotrimazole cream 1% on vaginal candidiasis.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016071929004N1

Enrollment

105

Registered

2016-10-12

Start date

2016-07-14

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vulvovaginal Candidiasis. Candidiasis of vulva and vagina

Interventions

Intervention 1: using one applicator of Essential oil of Anethum graveolens L. (Dill) vaginal cream (2%) every night for 7 nights. Intervention 2: using one applicator of Clotrimazole vaginal cream 1

Treatment - Drugs

using one applicator of Essential oil of Anethum graveolens L. (Dill) vaginal cream (2%) every night for 7 nights.

using one applicator of Clotrimazole vaginal cream 1% every night for 7 nights .

using one applicator of total extract of dill vaginal cream (2%) every night for 7 nights .

Eligibility

Sex/Gender

Female

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: sign and symptoms of vulvovaginal candidiasis; married women; between 18 to 65 years old; with positive sniff test; without pregnancy, without breast feeding, without chronic disease such as (kidney ,liver, cardiac disease and diabetes ), no existance of immunodeficiency nor complicated vaginal candidiasis on diagnosis of gynecologist and not using of systemic antibiotics and immunosuppressive drugs, or any vaginal drugs during the study and not using of systemic anti fungal drugs since 4 weeks ago. Exclusion criteria: side effects or drug reaction; pregnancy; menstruate; lack of patient's association.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Burning. Timepoint: at the beginning and 10 days after intervention. Method of measurement: Evaluation of clinical symptom's remission(burning) with VSQ (vulvovaginal symptom questionnaire).;Itching. Timepoint: at the beginning and 10 days after intervention. Method of measurement: Evauation of clinical symptom's remission (itching) with VSQ (vulvovaginal symptom questionnaire).;Vaginal discharge. Timepoint: at the beginning and 10 days after intervention. Method of measurement: Evaluation of clinical symptom's remission (vaginal discharge) with VSQ (vulvovaginal symptom questionnaire).;Erithema. Timepoint: at the beginning and 10 days after intervention. Method of measurement: physical exam.;Edema. Timepoint: at the beginning and 10 days after intervention. Method of measurement: physical exam.	—

Measure

Time frame

Burning. Timepoint: at the beginning and 10 days after intervention. Method of measurement: Evaluation of clinical symptom's remission(burning) with VSQ (vulvovaginal symptom questionnaire).;Itching. Timepoint: at the beginning and 10 days after intervention. Method of measurement: Evauation of clinical symptom's remission (itching) with VSQ (vulvovaginal symptom questionnaire).;Vaginal discharge. Timepoint: at the beginning and 10 days after intervention. Method of measurement: Evaluation of clinical symptom's remission (vaginal discharge) with VSQ (vulvovaginal symptom questionnaire).;Erithema. Timepoint: at the beginning and 10 days after intervention. Method of measurement: physical exam.;Edema. Timepoint: at the beginning and 10 days after intervention. Method of measurement: physical exam.

—

Secondary

Measure	Time frame
Sniff test outcome. Timepoint: at the beginning and 10 days after intervention. Method of measurement: vaginal smear.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZohreh Sarhadinejhad

Kerman University Of Medical Sciences

z_sarhadinejhad@kmu.ac.ir; dr_isac1390@ yahoo.com00983433122020; 00983433122023; 00983431325720

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026