The Comparison of the amount of pain from immediate and delayed palatal injection following buccal infiltrate injection using two anesthetic drugs

The Comparative Study of the Amount of Pain from Palatal Injection Immediately and with a Delay Following Buccal Infiltrate Injection with Two Anesthetic Agents, Lidocain and Articain in Patients Requiring Restorative Treatment of Maxillary Premolar Teeth

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016071817880N4

Enrollment

Registered

2017-02-21

Start date

2017-02-25

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Local anaesthetics. Local anaesthetics

Interventions

Intervention 1: Intervention group 1: Palatal injection of lidocain 2% with Epinephrine 1:80000, 10 min after buccal injection of articain 4% with Epinephrine 1:100000. Intervention 2: Intervention g

Treatment - Other

Intervention group 1: Palatal injection of lidocain 2% with Epinephrine 1:80000, 10 min after buccal injection of articain 4% with Epinephrine 1:100000

Intervention group 2: Palatal injection of lidocain 2% with Epinephrine 1:80000, 10 min after buccal injection of lidocain 2% with Epinephrine 1:80000

Control group 1: Palatal injection of lidocain 2% with Epinephrine 1:80000, immediately after buccal injection of articain 4% with Epinephrine 1:100000

Control group 2: Palatal injection of lidocain 2% with Epinephrine 1:80000, immediately after buccal injection of lidocain 2% with Epinephrine 1:80000

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: people with ages of 18 to 50 years and in good health; needing restorative treatment of maxillary premolar teeth. Exclusion criteria: the use of anesthetic drugs and sedatives and antidepressants during two weeks before the injection; allergic reactions to local anesthetic; edentulous at the premolar region of maxilla; medical history of cardiovascular and kidney diseases; any active pathology at the injection site; gastrointestinal bleeding or ulceration; pregnant and nursing patients.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The intensity of pain. Timepoint: Immediately after the buccal and palatal injection. Method of measurement: Based on the Visual Analogue Scale (VAS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam FarAra

Kermanshah Dentistry School

maryam.farara.ir@gmail.com+98 83 3722 2400

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026