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Compareing effects of venlafaxine and Placebo on depression, withdrawal symptoms, craving

The efficacy of venlafaxine in the treatment of depression, withdrawal symptoms, craving for methamphetamine compared with placebo (clinical trial with a control group)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160717028967N8
Enrollment
66
Registered
2018-06-30
Start date
2018-07-21
Completion date
Unknown
Last updated
2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Addiction. Mental and behavioral disorders due to use of other stimulants, including caffeine: dependence syndromes

Interventions

Intervention 1: Intervention group: The group will receive duloxetine treatment in two months. Intervention 2: Control group: The control group will receive placebo treatment in two months.

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Gender Male Methamphetamine dependence diagnoses accordingly Diagnostic and Statistical Manual of Mental Disorders fifth edition The dominant use of methamphetamine for at least 6 months lack of serious psychiatric disorders

Exclusion criteria

Exclusion criteria: Gender female No use of other drugs and stimulants at the time of entering the study The absence of comorbid psychiatric disorders symptoms

Design outcomes

Primary

MeasureTime frame
Depression. Timepoint: before intervention- 4 weeks later- 8 weeks later. Method of measurement: Depression Inventory.;Withdrawal symptoms. Timepoint: before intervention- 4 weeks later- 8 weeks later. Method of measurement: Inventory withdrawal symptoms.;Craving. Timepoint: before intervention- 4 weeks later- 8 weeks later. Method of measurement: Craving Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaezeh Tatari

Kermanshah University of Medical Sciences

tatari@yahoo.com+98 83 3826 4513

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026