bleeding. Other postprocedural disorders of circulatory system, not elsewhere classified
Conditions
Interventions
Intervention 1: Intervention group: patients receiving 1 gram TA diluted in 50 cc normal saline poured into mediastinal cavity before closing the chest. Intervention 2: Control group: patients receivi
Treatment - Drugs
Intervention group: patients receiving 1 gram TA diluted in 50 cc normal saline poured into mediastinal cavity before closing the chest
Control group: patients receiving 50 ml normal saline poured into mediastinal cavity before closing the chest
Sponsors
investigator
Eligibility
Sex/Gender
All
Age
20 Years to 90 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients undergoing CABG surgery alone; interrupting aspirin three days and Plavix at least five days before surgery; lack of consuming any other anticoagulant drugs such as heparin or warfarin; lack of coagulation and bleeding disorders; lack of liver and kidney disease; Ejection fraction> 35%. Exclusion criteria: complex surgery; emergency surgery; anticoagulation therapy before surgery; having hemoglobin lower than 8 grams per deciliter before surgery.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative bleeding. Timepoint: 24 hrs and 48 hrs postoperatively. Method of measurement: drainage in chest tube. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Mirmohammadsadeghi
Isfahan University of Medical Sciences
Outcome results
None listed