Comparison of the effect of Quetiapine and Alprazolam on insomnia after coronary artery bypass graft sugery

Comparison of the effect of Quetiapine and Alprazolam on sleep in patients who complain of insomnia after CABG (coronary artery bypass graft) surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160716028945N4

Enrollment

Registered

2018-11-07

Start date

2017-04-21

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insomnia. Other insomnia

Interventions

Intervention 1: Intervention group: 32 patients recieve half of TRANQOPINE 25mg tablet, every nights 30 minutes before sleep, from 3 days after surgery until 14 days after surgery. Intervention 2: Con

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient should undergo CABG and complain of insomnia after surgery

Exclusion criteria

Exclusion criteria: Unstable medical conditions History of psycological disease Dementia Acute narrow angle glaucoma Hypersensitivity to drug

Design outcomes

Primary

Measure	Time frame
Insomnia score according to (ISI) questionnaire. Timepoint: Three days after surgery(before intervention) and fourteen days after surgery. Method of measurement: (ISI) insomnia questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Mirmohammadsadeghi

Esfahan University of Medical Sciences

am_sadeghi@med.mui.ac.ir+98 31 3260 0961

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026