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Effects of calcium in the prevention of ovarian hyperstimulation syndrome in patients undergoing IVF/ICSI

Infusion of calcium gluconate for Prevention of Ovarian Hyperstimulation Syndrome in IVF cycle

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016071428930N1
Enrollment
186
Registered
2017-01-05
Start date
2016-04-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ovarian hyperstimulation. Hyperstimulation of ovaries

Interventions

Intervention 1: High risk infertile women in ivf cycle for OHSS (more than 20 follicles in both ovaries during oocyte retrieval) were randomly divided into two groups.control group receiv
Treatment - Drugs
High risk infertile women in ivf cycle for OHSS (more than 20 follicles in both ovaries during oocyte retrieval) were randomly divided into two groups.control group received ./5mg/day dop
Intervention group received ./5mg/day dopamine agonist (cabergolin) twice aday at day of HCG injection till 5 days and intravenous infusion of 10 mL 10% calcium gluconate in 200 mL 0.9% saline soluti

Sponsors

Vice Chancellor Of Research, Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Patients at high risk of ovarian hyperstimulation : PCO; patients having more than 20 follicles> 12 mm during oocyte retrieval; History of OHSS in previous cycles;Estradiol levels over 2500 on the day of HCG administration. Exclusion criteria: Diabetes ; Hypertension ;Asthma ;Blood pressure and Heart disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Prevention of OHSS. Timepoint: From strat to 2 weaks later. Method of measurement: Clinical signs and sonography Transvaginal.

Secondary

MeasureTime frame
Severity of OHSS. Timepoint: From start to 15 days later. Method of measurement: Clinical signs and Transvaginal sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Nayyereh khadem

Mashhad University of Medical Sciences

khademn@mums.ac.ir+98 51 3801 2607

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026