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The effect of selenium supplementation on lipid profile, anemia and inflammation indices

The effect of selenium supplementation on lipid profile, anemia and inflammation indices in patients undergoing peritoneal dialysis: A placebo-controlled clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160713028901N4
Enrollment
90
Registered
2020-11-08
Start date
2020-10-22
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peritoneal Dialysis. End stage renal disease

Interventions

Intervention 1: Intervention group: Treated with 200 micrograms alpha brand selenium tablets, every afternoon for 3 consecutive months. Intervention 2: Control group: Treated with placebo tablets dail

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients undergoing peritoneal dialysis over 18 years of age At least three months have passed since the first dialysis session Satisfied with the study

Exclusion criteria

Exclusion criteria: Having active hepatitis (according to several studies, selenium levels decrease in patients with hepatitis B and C) Normal serum selenium levels Taking steroidal and non-steroidal anti-inflammatory drugs within two months before the start of the study Take selenium supplements within two months of starting the study Insufficient incompatibility to consume the product

Design outcomes

Primary

MeasureTime frame
Serum selenium levels. Timepoint: Before the start and after the end of 3 months. Method of measurement: Serum selenium level of patients by atomic electron normal absorption method with graphite furnace using unicam929-uk device made by variant company in USA.;Lipid profiles (including total cholesterol, LDL, HDL, and TG). Timepoint: Before the start and after the end of 3 months. Method of measurement: By standard laboratory methods.;Indicators associated with anemia. Timepoint: Before the start and after the end of 3 months. Method of measurement: By standard laboratory methods.;Iinflammation. Timepoint: Before the start and after the end of 3 months. Method of measurement: By standard laboratory methods.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShirinsadat Badri

Esfahan University of Medical Sciences

badri@pharm.mui.ac.ir00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026