Coronary Artery Disease. Atherosclerosis
Conditions
Interventions
Intervention 1: 200 ml Of Milk Prepared With 2.5% Flaxseed Oil (containing 2 g alpha linolenic acid)/day For 2 Months. Intervention 2: 200 ml Of Skimmed Milk/Day For 2 Months.
Lifestyle
200 ml Of Milk Prepared With 2.5% Flaxseed Oil (containing 2 g alpha linolenic acid)/day For 2 Months
200 ml Of Skimmed Milk/Day For 2 Months
Sponsors
Office Of The Vice Chancellor For Research Of Tabriz University Of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:angiographically confirmed coronary artery disease with more than 50% stenosis of at least one of the major coronary vessels; subjects with 30-60 years old; BMI equal 20-30 kg/m2 ?Exclusion criteria:Miocardial infarction; Heart failure (function class III and IV), Heart valve diseases; Diabetes or any other chronic disease; Consumption of any immunosuppressive drugs; Antioxidant and/or vitamin supplements; Fish oil or (n-3) fatty acid supplements; Weight loss drugs or weight loss surgery; Smoking and drug users; Pregnant and lactating women; Those with Lactase deficiency( milk intolerance)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Levels Of Long Chain Fatty Acids. Timepoint: Pre And Post Intervention. Method of measurement: Gas Chromatography.;Lipid Profile. Timepoint: Pre And Post Intervention. Method of measurement: Enzymatic Method.;Arachidonoyl Ethanolamide Level. Timepoint: Pre And Post Intervention. Method of measurement: HPLC.;CB1/CB2 m-RNA Expression Level. Timepoint: pre and post intervention. Method of measurement: Real Time PCR. | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation Between Body Fat Percentage And Arachydonoylethanolamine Level. Timepoint: Pre and post intervention. Method of measurement: Bioelectrical impedanse for body fat and HPLC for arachydonoylethanolamine level.;Appetite And Depression Situation. Timepoint: Pre And Post Intervention. Method of measurement: Visual Analouge Scale and BECK questionnaires.;Energy And Macronutrient Levels. Timepoint: Pre And Post Intervention. Method of measurement: Food Record Questionnaire.;Physical Activity Level. Timepoint: Pre And Post Intervention. Method of measurement: International Physical Activity Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSevda Saleh-Ghadimi
Faculty Of Nutrition And Food Science
Outcome results
None listed