Treatment of diabetic foot ulcer. Type 2 diabetes mellitus with circulatory complications
Conditions
Interventions
Intervention 1: Intervention group: Nanofibers containing doxycycline and venlafaxine were prepared from Nano Novin Polymer Factory (NATO MAND), then FTIR test was used to determine drug quantity and
Sponsors
Isfahan Research Department of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age between 45 and 65 years Having diabetic foot ulcers that have not recovered despite a treatment during the past month (2-7 cm) Having pain at rest and walking Signature written consent
Exclusion criteria
Exclusion criteria: Pregnancy or breastfeeding septicemia Other systemic kidney diseases, such as cancer, autoimmune diseases, blood diseases, liver disease and ... Hospitalization due to severe illness in the past two months Severe malnutrition The presence of ulcers at the feet of patients, except for diabetes, for example syphilis, tuberculosis, or fungal foot Any allergy to the compounds used in the production of scaffolding Having osteomyelitis in the diabetic foot History of previous wound in the same place
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Size of the Ulcer. Timepoint: Before starting the study, 2 weeks and in months of 1,2,12,18 after using drugs. Method of measurement: biopsy.;Distance walked without pain. Timepoint: Before starting the study, 2 weeks and in months of 1,2,12,18 after using drugs. Method of measurement: Meter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRokhsareh Meamar
Esfahan University of Medical Sciences
Outcome results
None listed