General surgery. General- and plastic-surgery devices associated with adverse incidents
Conditions
Interventions
Ondansetron 8 milligram intravenous infusion over a minute at a time in groups after surgery.
Diagnosis
Ondansetron 8 milligram intravenous infusion over a minute at a time in groups after surgery
Sponsors
Vice chancellor for research, Bushehr University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : patients over thirty years with no history of heart disease and patients who did not use medication to take effect on QT Interval. Exclusion criteria: patients with electrolyte imbalance such as low potassium ; patients with a history of heart disease such as myocardial infarction and heart failure ; patients who have prolonged use of drugs affecting the QT Interval ; if the use of pain pumps containing ondansetron and the drug narcotic, patient is excluded ; patients who receive antinausea and vomiting drugs during surgery and immediately after surgery due to severe nausea and vomiting ; patients who have any dysrhythmia in ECG ; all procedures with the risk of the emergence of nausea and vomiting such as: laparoscopy, Orchiopexy, Varicocelectomy, surgery of ear, nose and throat, eye surgery (strabismus) , surgery of neurosurgery (ICP above) and any intervention in order to create hypocapnia not included in this study ; patients who experience severe nausea and vomiting in previous surgeries are not included in this study ; patients who have a history of sudden death in family members will not be enrolled in this study ; patients who have a history of liver disease and liver enzyme abnormalities were excluded.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QTc Interval. Timepoint: The night before surgery, and 30 minutes after administration of ondansetron. Method of measurement: With electrocardiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHaghighi Rahmanian Ehsan
Bushehr University Of Medical Science
Outcome results
None listed