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The effect of intrauterine injection of human chorionic gonadotropin before embryo transfer on pregnancy outcomes in assisted reproductive cycles

Evaluation of the effect of intrauterine injection of human chorionic gonadotropin (HCG) before embryo transfer (ET) on pregnancy outcomes in assisted reproductive cycles (IVF / ICSI)

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160703028756N7
Enrollment
100
Registered
2021-10-16
Start date
2021-08-29
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility.

Interventions

Intervention group: In the intervention group, a 5000-unit vial of Karma brand with Karma brand is mixed with 0.4 ml of embryo glue and 40 µl of which is equivalent to 500 units of HCG is injected int

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Hip women under the age of 40 who have undergone IVF / ICSI treatment protocols are endocrine candidates for grade A or B embryos.

Exclusion criteria

Exclusion criteria: Azoospermia through sperm testing History of uterine surgery through history Severe endometriosis through history and ultrasound findings Hydrosalpinx by ultrasound or hysterosalpingography Endocrine disorders such as diabetes thyroid via blood biochemistry test History of operative hysteroscopy History of recurrent miscarriages More repeated failures equal to 3 times in the history

Design outcomes

Primary

MeasureTime frame
Follicle size. Timepoint: During embryo transfer and one week after embryo transfer. Method of measurement: sonography.;Type of embryo transferred. Timepoint: ---. Method of measurement: --.;Number of embryos transferred per cycle. Timepoint: Patient cycle. Method of measurement: Laboratory.;AMH. Timepoint: Before embryo transfer. Method of measurement: Laboratory.

Secondary

MeasureTime frame
Ongoing pregnancy. Timepoint: After embryo transfer. Method of measurement: Question from the patient.;Cilinical pregnancy. Timepoint: After embryo transfer. Method of measurement: Question from the patient.;Chemical pregnancy. Timepoint: After embryo transfer. Method of measurement: Question from the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Naghshineh

Esfahan University of Medical Sciences

naghshineh@med.mui.ac.ir+98 31 3236 2191

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026