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The effect of premedication on post root canal therpy pain

Comparison of the effect of premedication with two drugs:oral Dextrometorphan and Ibuprofen on post root canal therapy pain in pateints with irriversible pulpitis in first mandibular molar.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016070228732N1
Enrollment
45
Registered
2017-04-23
Start date
2017-04-09
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Toothache. Atypical facial pain

Interventions

Intervention 1: intervention:oral Dextrometorphan,30 mgr,single dose,1 hour before root canal therapy. Intervention 2: intervention:oral Ibuprofen,600 mgr,single dose,one hour before root canal therap
Treatment - Drugs
intervention:oral Dextrometorphan,30 mgr,single dose,1 hour before root canal therapy.
intervention:oral Ibuprofen,600 mgr,single dose,one hour before root canal therapy.
control:placebo,single dose,one hour before root canal therapy.

Sponsors

Isfahan Islamic Azad University khorasgan branch
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with systemic health; suffered from irreversible pulpitis with spontaneous pain in the lower first molar; The patient didn't get analgesics 12 hours before the treatment ; Have only one painful tooth; Tooth without radiographic radiolucency; viewing vital pulp during access cavity preparation; Possibility of completing treatment in one visit. Exclusion criteria:Patients with systemic disease; patients who took analgesics 12 hours before the treatment; Teeth with apical radiographic radiolucency ;necrotic tooth; Not possible to complete the treatment in one visit.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain after root canal therapy. Timepoint: 2,4,6,8 hours after intervention. Method of measurement: Visual Analog Scaling.

Secondary

MeasureTime frame
. Timepoint: . Method of measurement: .

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElmira Ahmadpour

Isfahan Islamic Azad University khorasgan branch

e.ahmadpour@khuisf.ac.ir+98 383334191

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026