essential hand tremor. Essential tremor
Conditions
Interventions
Intervention 1: Dysport intramuscular injection in forearm 100-150 unit once. Intervention 2: tablet propranolol 40-160 mg daily for 3 months.
Treatment - Drugs
Dysport intramuscular injection in forearm 100-150 unit once
tablet propranolol 40-160 mg daily for 3 months
Sponsors
Vice chancellor for research, army university of medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: essential hand tremor with severity equal or greater than 2 according to tremor research group essential tremor rating assessment scale (TETRAS) version 3.1 (paragraph 4); normal thyroid function test; age higher than 18 years; exclusion criteria: drug induced tremor; pregnancy and lactation; allergy to cow milk protein; propranolol contraindications for example heart block, congestive heart failure, diabetes melitus, asthma and etc; history of botulinum injection in upper limb; recent botulinum injection in any part of body since 8 months ago; allergy to botulinum; history of myasthenia gravis or suspicious to myasthenia gravis; parkinson disease; use of anti-dopaminergic medications
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hand tremor severity. Timepoint: before treatment, one and two and three months following the start of treatment. Method of measurement: tremor research group essential tremor rating assessment scale (TETRAS).;Quality of life. Timepoint: before treatment, two months following start of treatment. Method of measurement: short form 36 (SF-36) quality of life questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: one and two and three months following start of treatment. Method of measurement: history taking. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaeed Amiri
Army university of medical sciences
Outcome results
None listed