hypertension. Essential (primary) hypertension
Conditions
Interventions
Intervention 1: Intervention group: Daily consumption of 10 gram of barberry powder for 8 weeks. Barberry is purchased from the local market at one time. Intervention 2: Control group: Daily consumpti
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Willingness to participate in the study Age between 20-65 years Having elevated blood pressure (129/ < 85) or known hypertensive patients on medical treatment At least one other classical cardiovascular disease risk factors, including hyperlipidemia or diabetes mellitus
Exclusion criteria
Exclusion criteria: BMI> 30 Patients on nitrate drugs High doses of statins consumption (Atorvastatin>40 mg/day or Rosuvastatin>20 mg/day) Regular consumption (more than once in a week) of vitamins or minerals supplements during past month Chronic kidney disease stage 4 or 5
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Flow mediated dilation (FMD). Timepoint: Baseline and the end of the study. Method of measurement: sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma ICAM-1. Timepoint: Baseline and the end of the study. Method of measurement: ELISA.;Plasma VCAM-1. Timepoint: Baseline and the end of the study. Method of measurement: ELISA. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHadi Emamat
Shahid Beheshti University of Medical Sciences
Outcome results
None listed