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Comparison of effects of refined olive oil and canola in patients referred for coronary angiography

Comparison of effect of refined olive oil with canola oil consumption on plasma lipids and inflammatory cytokines secretion of whole blood culture in patients referred for coronary angiography

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160702028742N5
Enrollment
40
Registered
2019-04-19
Start date
2019-01-01
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease. Atherosclerotic heart disease of native coronary artery

Interventions

Intervention 1: Intervention group: Daily consumption of 25 mL of pure canola oil as cold with meals for 6 weeks. Intervention 2: Intervention group: Daily consumption of 25 mL of refined olive oil as

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: Existence of at least one of the major cardiovascular risk factors Willingness to participate in the study No consumption of any anti-inflammatory or antioxidant supplement such as omega-3, vitamin E, vitamin C and Selenium in last month

Exclusion criteria

Exclusion criteria: Unwillingness to continue Any changes in disease treatment plan such as changes in medical treatment or surgery Existence of gastrointestinal complications such as diarrhea

Design outcomes

Primary

MeasureTime frame
Lipoprotein-associated phospholipase A2 (Lp-PLA2). Timepoint: Baseline and the end of the study. Method of measurement: ELISA.

Secondary

MeasureTime frame
Plasma Lipoproteins. Timepoint: Baseline and the end of the study. Method of measurement: colorimetry.;Interleukin-6 (IL-6) & Monocyte Chemoattractant Protein-1 (MCP-1) in cultured whole blood. Timepoint: Baseline and the end of the study. Method of measurement: ELISA.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNafiseh Khandouzi

Shahid Beheshti University of Medical Sciences

n-khandouzi@sbmu.ac.ir+98 21 2207 7424

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 17, 2026