Effect of zinc and vitamin E supplements on immune system cytokines

Effect of co-administration of zinc and vitamin E supplements on plasma concentrations cytokines secreted by T-helper1, 2, and 17 in cardiac surgery patients: Randomized controlled trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160702028742N12

Enrollment

Registered

2022-09-03

Start date

2022-08-27

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary heart disease.

Interventions

Intervention 1: Control group: Placebo capsules produced by the pharmaceutical company producing the study supplements (Dana Pharmaceutical Company) and contain all the ingredients used in the supplem

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients who are candidates for open heart surgery

Exclusion criteria

Exclusion criteria: Off-pump heart surgery

Design outcomes

Primary

Measure	Time frame
Interleukin 17 interferon gamma concentration. Timepoint: Measurement of cytokine concentration at the beginning of the study (before surgery) and 21 days after surgery. Method of measurement: ELISA.	—

Secondary

Measure	Time frame
Post surgery length of hospitalization. Timepoint: After open heart surgery. Method of measurement: Medical record.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Makiabadi

Shahid Beheshti University of Medical Sciences

elham.maki.71@gmail.com+98 21 2236 0658

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026