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Comparison of the effect of Fennel capsule and Vitamin E capsule on menopausal symptoms in women

Comparison of the effect of Fennel capsule and Vitamin E capsule on menopausal symptoms in women:a randomized placebo-controlled clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160630028717N4
Enrollment
105
Registered
2024-03-16
Start date
2024-04-03
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menopausal symptoms. Menopausal and female climacteric states

Interventions

Intervention 1: Intervention group: The fennel capsule group in this study will receive 30 mg Fennelin soft capsules (standardized to 21-27 mg of Antole) twice a day for 8 weeks orally. Fennelin soft

Sponsors

Guilan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to No maximum

Inclusion criteria

Inclusion criteria: Willingness to participate in the study and sign a written informed consent form At least ability to read and write Women with normal menopause and age over 40 years Lapse of at least12 months since the last menstruation, according to the Stages of Reproductive Aging Workshop+ 10 (STRAW+10) criteria Menopause less than 5 years (according to the person's statement) Having a score of 9 and above on the Menopause Rating Scale (MRS)

Exclusion criteria

Exclusion criteria: History of respiratory disease (asthma and allergy), kidney disease, coagulation disease, hemophilia, inflammatory disease, liver disease and gallstones, cancer, epilepsy/seizures, and uterine diseases (such as fibroids, adenomyosis, and endometriosis). Allergy reaction to celery and fennel Taking immunosuppressive drugs, anticoagulants (such as warfarin and heparin), neuropsychiatric drugs, antioxidant supplements, herbal drugs, and hormone therapy Smoking and alcohol consumption Stressful factors (such as the death of a first-degree relative in the last 6 months and job loss)

Design outcomes

Primary

MeasureTime frame
Menopausal symptoms score. Timepoint: Before the intervention, 4 and 8 weeks after the intervention. Method of measurement: Menopause Rating Scale (MRS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParvaneh Rezasoltani

Guilan University of Medical Sciences

rezasoltani49@gmail.com+98 13 3355 5056

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026