Subclinical hypothyroidism. Iodine-deficiency-related (endemic) goitre, unspecified
Conditions
Interventions
For patients, vitamin D (50,000 IU capsule per week for 8 weeks) is recommended..
Treatment - Drugs
For patients, vitamin D (50,000 IU capsule per week for 8 weeks) is recommended.
Sponsors
Vice Chancellor for Research of Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Criteria for this study: women over 18 years old; patients with subclinical hypothyroidism with TSH higher than 4.5 mlu / L and less than 10 mlu / L; patients with vitamin D deficiency who are defined with 25 (OH) D3 less than 30 mlu / L. Exclusion criteria: patients with systemic diseases (Kidney - lung - Haematic - Digestive); taking medicatiobs that affect on the metabolism of vitamin D; older than 65 years old or younger than 18 years old; being pregnant or plan to become pregnant; patient dissatisfaction to participate in the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thyroid-stimulating hormone(TSH). Timepoint: Baseline and 3 months after treatment. Method of measurement: Test.;Vitamin D. Timepoint: Baseline and 3 months after treatment. Method of measurement: Test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Thyroid Function (FT4). Timepoint: Baseline and 3 months after treatment. Method of measurement: Test.;Thyroid peroxidase antibody. Timepoint: Baseline and 3 months after treatment. Method of measurement: Test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Farzad Najafipour
Tabriz University of Medical Sciences
Outcome results
None listed