obesity. Obesity due to excess calories
Conditions
Interventions
Intervention 1: The intervention group 1: candy contains about 1 gram of Portulaca oleracea, 0.5 grams of Plantago major, 0.5 grams of Alcea leaves, 1 g peanut oil and the rest is up to 4 g excipien
Treatment - Drugs
Placebo
The intervention group 1: candy contains about 1 gram of Portulaca oleracea, 0.5 grams of Plantago major, 0.5 grams of Alcea leaves, 1 g peanut oil and the rest is up to 4 g excipient.Half an hour b
The intervention group 2: 150 mg tablets (Bupropion)once daily for 8 weeks
Control group: the calorie of control group candy is similar but contains only excipient.Half an hour before each meal will be sucked a candy.3 times a day for 8 weeks
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:Within last 3 months do not have intervention for weight loss? Body mass index higher than 27? People within the age 70-18 years Exclusion criteria: Certain diseases that need to expedite the treatment regimen? Rapid changes in body weight (more than kg5 in the last 3 months)? Taking drugs that affect blood glucose levels and lipid profile? Taking appetite-lowering drugs? Diabetes and lipid profile disorders that is in need of medical treatment? The risk of possible side effects (such as gastroesophageal reflux disease)? Having a history of seizures or taking anticonvulsant drugs? Anorexia or Bulimia history? Psychopathy? Cardiovascular disease and hypertension and other chronic diseases? A history of alcohol consumption and smoking? History of taking antidepressant drugs in the last 6 months
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Appetite. Timepoint: It is compeleted 3 times per week for 8 weeks, before taking the candy, 30 minutes, 1 hour and 2 hours after it. Method of measurement: (VAS)visual analogue scale questionnaire.;Diet information. Timepoint: Week of 0,4 and 8. Method of measurement: 3-day food record questionnaire.;Anthropometric indices. Timepoint: Week of 0 and 8. Method of measurement: Meter, Scale.;Blood pressure. Timepoint: Week of 0 and 8. Method of measurement: Manometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood glucose. Timepoint: Week of 0 and 8. Method of measurement: Laboratory method.;Lipid profile. Timepoint: Week of 0 and 8. Method of measurement: Laboratory method.;Liver enzymes. Timepoint: Week of 0 and 8. Method of measurement: Laboratory method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contact(MD-PhD)Nematy Mohsen
Mashhad University of Medical Sciences
Outcome results
None listed