Vesicoureteral reflux. Vesicoureteral-reflux-associated uropathy
Conditions
Interventions
Intervention 1: In the intervention group, 1 cc of the lyophilized autologous prepuce will be injected in the submucosal area of the orifice of the ureter through endoscopic procedure in operating roo
Treatment - Drugs
In the intervention group, 1 cc of the lyophilized autologous prepuce will be injected in the submucosal area of the orifice of the ureter through endoscopic procedure in operating room.
In the control group, 1 cc of deflux as the gold standard will be injected in the submucosal area of the orifice of the ureter through an endoscopic procedure in operating room.
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
6 Months to 13 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Vesicoureteral reflux grade 2-5 based on clinical and paraclinical evidence; Having the indication for stretching material endoscopic injection. Exclusion criteria: Having deflux contraindications based on the protocols announced by the deflux producer; Having the indication for stretching material endoscopic injection; Having prohibition of operation according to consultation with anesthesiologist and heart expert; Children with 1st grade reflux grade 1 and recurrent or febrile urinary tract infection
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary Tract Infection. Timepoint: 3, 6, and 9 months after intervention. Method of measurement: Urinary culture.;The rate of urine rejection (return) from the bladder to the ureter. Timepoint: Before and 3, 6, and 9 months after intervention. Method of measurement: VCUG. | — |
Secondary
| Measure | Time frame |
|---|---|
| -. Timepoint: -. Method of measurement: -. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr MJ.Mohseni
Tehran University of Medical Sciences
Outcome results
None listed