Comparison of pain reduction between lidocaine and articaine for anesthesia in extraction of molar teeth

Comparison of pain reduction between lidocaine and articaine for anesthesia of the second primary molar, requiring pulp therapy, a Randomized Clinical Trial.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016062627111N2

Enrollment

130

Registered

2016-08-21

Start date

2016-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Local Anasthesia. Local anaesthetics

Interventions

Intervention 1: Infiltrative injection of 4% articaine carpule with epinephrine 1:100000 and measuring of pain perception at the time of injection by using visual analogue pain scale and onset time of

Treatment - Drugs

Infiltrative injection of 4% articaine carpule with epinephrine 1:100000 and measuring of pain perception at the time of injection by using visual analogue pain scale and onset time of anesthesia in o

Infiltrative injection of 2% lidocaine carpule with epinephrine 1:100000 and measuring of pain perception at the time of injection by using visual analogue pain scale in one-minute intervals by using

Eligibility

Sex/Gender

All

Age

21 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: volunteers requiring pulp therapy with intact maxillary molar that response to pulp tester; individuals who can use visual analogue pain scale. Exclusion criteria: patients with periodontal disease; positive history of alcohol consumption; cigarette smoking; drug user; patients who have received antidepressant or steroid analogues drug during the 48 hours before study; pregnant patients; patients with known allergy to lidocaine or epinephrine; peripheral neuropathy, positive history of dental phobia or any damage to teeth

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Onset time of anesthesia. Timepoint: 1 minute intervals. Method of measurement: Patient Self Recall.	—

Secondary

Measure	Time frame
Severity of pain during injection. Timepoint: Immediately after the injection. Method of measurement: Visual analogue pain scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarshid Rayati

Qazvin University of Medical Sciences

farshidrayati@yahoo.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 6, 2026