Effect of chewing gum on saliva materials in children with severe caries

Effect of chewing gum containing CPP-ACP on salivary concentration of calcium , phosphate and alkaline phosphatase in 7-11 years old children with severe caries

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016062528624N1

Enrollment

Registered

2016-07-15

Start date

2015-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

salivary concentration of calcium , phosphate and alkaline phosphatase. Dental examination

Interventions

Intervention 1: Intervention: trident gum, 20 minutes of chewing,Sampling 5 minutes after chewing gum. Intervention 2: Control: Intervention: trident gum, 20 minutes of chewing,Sampling 5 minutes afte

Diagnosis

Intervention: trident gum, 20 minutes of chewing,Sampling 5 minutes after chewing gum

Control: Intervention: trident gum, 20 minutes of chewing,Sampling 5 minutes after chewing gum

Intervention: trident gum, 20 minutes of chewing,Sampling 20 minutes after chewing gum

control: trident gum, 20 minutes of chewing,Sampling 20 minutes after chewing gum

Eligibility

Sex/Gender

All

Age

89 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: No caries in the first group; tooth decay at least 6 to Group II. Exclusion criteria: Any repeort of systemic diseases; History of radiotherapy and chemotherapy; Anticholinergic drugs; Lack of cooperation during the study; Using medication within 2 hours before sampling

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Calcium. Timepoint: 5 and 20 minutes after chewing gum. Method of measurement: with laboratory analysis.;Phosphate. Timepoint: 5 and 20 minutes after chewing gum. Method of measurement: with laboratory analysis.;Alkaline phosphatase. Timepoint: 5 and 20 minutes after chewing gum. Method of measurement: with laboratory analysis.	—

Secondary

Measure	Time frame
Calcium. Timepoint: 5 and 20 minutes after chewing gum. Method of measurement: with laboratory analysis.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAvin Fattahi

Islamic Azad University of Isfahan (Khorasgan), Dental School

a.fattahi@khuisf.ac.iravinfattahi64@gmail.com+98 31 3535 4053

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026