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The effects of Multi Minerals (Zn, Mg and Ca) and Vitamins (C and E) Supplementation in the Prevention of Preeclampsia

The effects of Multi Minerals (Zn, Mg and Ca) and Vitamins (C and E) Supplementation in the Prevention of Preeclampsia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016062528617N1
Enrollment
90
Registered
2016-09-24
Start date
2015-03-16
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preeclampsia. O14.9

Interventions

Intervention 1: The first group receives one tablet multi minerals (Claci-care that contained 800 mg calcium, 200mg magnesium and 8mg zinc) per day. Follow up: The patients from 20 weeks to 28 weeks o
Treatment - Drugs
The first group receives one tablet multi minerals (Claci-care that contained 800 mg calcium, 200mg magnesium and 8mg zinc) per day. Follow up: The patients from 20 weeks to 28 weeks of gestation mont
The second group receives 250 mg vitamin C and 55 mg vitamin E. Follow up: The patients from 20 weeks to 28 weeks of gestation monthly, from weeks 28 to 36 on a fortnightly and then weekly basis until
The third group was the control group who only receives ferrous sulfate (which is only for pregnant women). Follow up: The patients from 20 weeks to 28 weeks of gestation monthly, from weeks 28 to 36

Sponsors

Ilam University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria included women with at least one of the risk factors for preeclampsia (including chronic vascular disease, multiple pregnancy, history of preeclampsia at or near the previous pregnancy, history of thrombophilia or APA syndrome, high maternal age, obesity, etc.); in the second half of pregnancy (20 weeks gestation or later). Exclusion criteria included lack of cooperation; intake of multi mineral and vitamin in the control group.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The incidence of preeclampsia. Timepoint: The patients from 20 weeks to 28 weeks of gestation monthly, from weeks 28 to 36 on a fortnightly and then weekly basis until the delivery were visited in Mostafa Khomeini’s Hospital for blood pressure and in the Laboratory of Imam Khomeini’s Hospital for their proteinuria. Method of measurement: Preeclampsia is described with the signs such as the minimum standards hypertension after 20 weeks of pregnancy and proteinuria of =300 mg per 24 hours or equal to +1 in urine dipstick.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMilad Azami

Student Research Committee, Ilam University of Medical Sciences, Ilam, Iran

milad98azami@gmail.com+98 938 031 6334

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026