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The effect of nigella sativa+pepper nigrum on infertility in women with PCOS

Comparison of the effects of nigella sativa +pepper nigrum (nigrum Piper )with letrozole + tamoxifen in infertile woman with polycystic ovary syndrom

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016062121653N6
Enrollment
90
Registered
2017-03-18
Start date
2015-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertile women with polycystic ovarian syndrom.

Interventions

Treatment - Drugs
Intervention 1: Intervention1: Tab tamoxifen 10mg (two tablet per day) +Tab letrozole 2/5mg (two tablet per day) from third to eighth day of menstrual cycle. Intervention 2: Intervention 2: cap powde
Intervention1: Tab tamoxifen 10mg (two tablet per day) +Tab letrozole 2/5mg (two tablet per day) from third to eighth day of menstrual cycle
Intervention 2: cap powder of nigella 550 mg+cap powder of pepper 550 mg(po Q8h) from third to eighth day of menstrual cycle for three month

Sponsors

Jahrom University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criterion: infertile women with poly cystic ovary syndrome who are not pregnant after 12 months of unprotected intercourse. Exclusion criteria: women with other causes of infertility such as endometriosis or other surgical or internal problems who have not PCOS criteria. also,women who have evidence of ohss in primary sonography.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Follicle size. Timepoint: Eighth and twelfth day of menstural cycle. Method of measurement: Sonography.;Number of follicles. Timepoint: eighth and twelfth day of menstural cycle. Method of measurement: sonography.;Endometrial thickness. Timepoint: eighth and twelfth day of menstural cycle. Method of measurement: sonography.

Secondary

MeasureTime frame
Ovarian hyper stimulation syndrom. Timepoint: In the entire course of treatment. Method of measurement: Sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Rasekh Jahromi Athar

Jahrom University of Medical Sciences

Drrasekh@yahoo.com+98 71 5422 1040

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026