Effect of Cervical Spine Manual Therapy on the Electrophysiological Findings in the Migraineur Subjects with Neck Pain

The Effect of Upper Cervical Spine Manual Therapy on the Clinical and Physical Signs and Symptoms, Disability, and Electrophysiological Findings in the Migraineur Subjects with Neck Pain

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160621028567N2

Enrollment

Registered

2021-03-10

Start date

2021-04-04

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Migraine. Condition 2: Neck Pain. Migraine Cervical root disorders, not elsewhere classified

Interventions

Intervention 1: Intervention group: upper cervical spine manual therapy in 4 sessions. To perform manual therapy, the patient will be in a supine position and the physiotherapist will stand above the

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Migraine according to IHS criteria at least three days a month Neck pain (more than 30% NDI and at least one symptomatic segment according to PAIVMs in the upper cervical spine) with migraine Age between 18 and 50 years

Exclusion criteria

Exclusion criteria: Other primary or secondary headaches Other neurological diseases Severe physical / psychiatric limitations Ear disorders Medication Overuse Headache Systemic diseases such as fibromyalgia or rheumatoid arthritis Vertebrobasilar insufficiency / atherosclerosis of cervical arteries Cervical spine instability and alar and transverse ligament defects Nerve blocks in the last 6 months Neck and shoulder physiotherapy treatments in the last 6 months Malignancies

Design outcomes

Primary

Measure	Time frame
Headache Intensity. Timepoint: At the beginning of the study, one month after end of interventions. Method of measurement: Designed form for recording the clinical characteristics of headache.;Headache Frequency. Timepoint: At the beginning of the study, one month after end of interventions. Method of measurement: Designed form for recording the clinical characteristics of headache.;Pain killer medications. Timepoint: At the beginning of the study, one month after end of interventions. Method of measurement: Designed form for recording the clinical characteristics of headache.;Headache Duration. Timepoint: At the beginning of the study, one month after end of interventions. Method of measurement: Designed form for recording the clinical characteristics of headache.	—

Measure

Time frame

Headache Intensity. Timepoint: At the beginning of the study, one month after end of interventions. Method of measurement: Designed form for recording the clinical characteristics of headache.;Headache Frequency. Timepoint: At the beginning of the study, one month after end of interventions. Method of measurement: Designed form for recording the clinical characteristics of headache.;Pain killer medications. Timepoint: At the beginning of the study, one month after end of interventions. Method of measurement: Designed form for recording the clinical characteristics of headache.;Headache Duration. Timepoint: At the beginning of the study, one month after end of interventions. Method of measurement: Designed form for recording the clinical characteristics of headache.

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Secondary

Measure	Time frame
Wave I latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;Wave II latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;Wave III latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;Wave IV latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;Wave IV latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;I-III interpeak latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;III-IV interpeak latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;I-IV interpeak latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;R1 latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Blink Reflex.;R2 latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Blink Reflex.;R2 contralateral latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Blink Reflex.;Cervical flexion range of motion. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: iPhone compass application.;Cervical extension range of motion. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: iPhone compass application.;Cervical right rotation ran	—

Measure

Time frame

Wave I latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;Wave II latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;Wave III latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;Wave IV latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;Wave IV latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;I-III interpeak latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;III-IV interpeak latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;I-IV interpeak latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Brain Auditory Evoked Response.;R1 latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Blink Reflex.;R2 latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Blink Reflex.;R2 contralateral latency. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: Blink Reflex.;Cervical flexion range of motion. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: iPhone compass application.;Cervical extension range of motion. Timepoint: At the beginning of the study, one month after the end of the study. Method of measurement: iPhone compass application.;Cervical right rotation ran

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarid Bahrpeyma

Tarbiat Modares University

bahrpeyf@modares.ac.ir+98 21 8288 3819

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 9, 2026