Effect of vitamin D in prevention of postoperative hypocalcemia in total thyroidectomy patients

Effect of preoperative vitamin D supplementation on postoperative hypocalcemia in patients with vitamin D deficiency candidate for total thyroidectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016062016077N6

Enrollment

100

Registered

2016-06-29

Start date

2015-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative hypocalcemia. Postprocedural endocrine and metabolic disorders, not elsewhere classified

Interventions

Intervention 1: Vitamin D 50000 IU weekly for 4 week administration in intervention group. Intervention 2: Placebo administration instead of vitamin D in control group.

Treatment - Drugs

Placebo

Vitamin D 50000 IU weekly for 4 week administration in intervention group

Placebo administration instead of vitamin D in control group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: multi nodular goiter; thyroid cancers; patients candidates fo thyroidectomy who suffer moderate to severe vitamin D deficiency in preoperative tests. Exclusion criteria:previous history of head and neck surgeries: coexisting parathyroid diseases; suffering diseases that affect calcium and vitamin D metabolism; patients who have injured or dissected parathyroid glands during surgery; patients who received vitamin supplements before surgery.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Serum calcium level. Timepoint: Before surgery, 6 to 12 hours after surgery, 18 to 24 hours after surgery and 48 to 72 hours after surgery. Method of measurement: According to laboratory tests.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Ramouz

Tabriz University of Medical Sciences

ali.ramouz@gmail.com+98 41 3441 3895

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026