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Efficacy of black seed (Nigella sativa) on kidney stone dissolving

Study the effect of the product contains Black Seed on the bigger stones or equal to five millimetres in patients with kidney stones without metabolic or infectious risk factors.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160619028530N2
Enrollment
60
Registered
2018-02-20
Start date
2016-02-20
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

kidney stone. Calculus of kidney

Interventions

Intervention 1: Intervention group: Capsules of black seed (500 mg twice a day) were given to patients for 10 weeks. Capsules were taken with honey syrup. Intervention 2: Control group: Placebo capsul

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Men and women aged 20 to 60 years, people 20-60 years old with kidney stone disease that has been confirmed by ultrasound sonography Patients with kidney stones equal or larger than 5 mm diameter People who do not have poor renal and hepatic function (according to tests and records) people who are satisfied with traditional treatment

Exclusion criteria

Exclusion criteria: pregnancy breast feeding any renal disorder which requires new treatment protocols known allergy to black seed

Design outcomes

Primary

MeasureTime frame
Stone number. Timepoint: Before the intervention and 70 days after the start of taking the black seed. Method of measurement: Change in the number of stones after intervention by kidney ultrasound based on millimetres.;Stone size. Timepoint: Before the intervention and 70 days after the start of taking the black currant. Method of measurement: Change in the size of the stones after the intervention by kidney ultrasound based on millimetres.

Secondary

MeasureTime frame
The amount of calcium in the blood. Timepoint: Before the intervention and 70 days after the start of taking the black seed. Method of measurement: Photometric.;Ph level of urine. Timepoint: Before the intervention and 70 days after the start of taking the black seed. Method of measurement: pH meter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamad Reza Ardakani Movaghati

Mashhad University of Medical Sciences

ardakanimr1@mums.ac.ir+98 51 3854 3032

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026