Psychogenic vaginismus. Spasm of the pelvic floor muscles that surround the vagina, causing occlusion of the vaginal opening. Penile entry is either impossible or painful
Conditions
Interventions
Intervention 1: intervention group 1:injection of botulinum toxin (dysport ):500 unit is diluted in 1.5 cc N/S.150-400 U disport was equally injected in the puborectalis muscles ,3 points on each side
Treatment - Drugs
Rehabilitation
intervention group 1:injection of botulinum toxin (dysport ):500 unit is diluted in 1.5 cc N/S.150-400 U disport was equally injected in the puborectalis muscles ,3 points on each side with 23 needle.
Control group:Physiotherapy: relaxation exercises, biofeedback, desensitization and focus sensory (sensation focus) is used during weekly meetings.Patients initially trained in pelvic floor anatomy .
Sponsors
Vice Chancellor for research of Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: inclusion criteria:20-40 years old nonpregnant women of sexual health and women clinics of emem khomeini hospital which have grade 3 or 4 vaginismus on lamont grading; they dont have any botulinum toxin containdication( albumin and botulinum or injectable component alergy; infection of injection site; pregnancy; nerve and muscle desease such as Myasthenia Gravis and Lambert Eaton syndrome; coagulation disorders; anticoagulant drugs exclusion criteria:pregnant women; pregnancy planing; botulinum contraindication; poor cooperation; secondary vaginismus; Vvlvdynya; skin disorders of vulve or Perineum; anal fissure; urinary or deficatory disorders; infection of injection site; previous botulinum treatment; previous physiotherapy
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Libido. Timepoint: before and 1week after Treatment. Method of measurement: Demographic questionaries and women sexual function questionaries(FSFI).;Arousal. Timepoint: before and 1 week after Treatment. Method of measurement: Demographic questionaries and women sexual function questionaries(FSFI).;Lubrication. Timepoint: before and 1 week after Treatment. Method of measurement: Demographic questionaries and women sexual function questionaries(FSFI).;Orgasm. Timepoint: before and 1 week after Treatment. Method of measurement: Demographic questionaries and women sexual function questionaries(FSFI).;Sexual Satisfaction. Timepoint: before and 1 week after Treatment. Method of measurement: Demographic questionaries and women sexual function questionaries(FSFI).;Pain. Timepoint: before and 1 week after Treatment. Method of measurement: Demographic questionaries and women sexual function questionaries(FSFI). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactTahereh Eftekhar dr
Tehran University Of Medical sciences
Outcome results
None listed