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Savory effect of mucositis and pain severity in children receiving chemotherapy: a randomized double-blind clinical trial.

The effect of Satureja Hvrtnsz (carvacrol) on the severity of mucositis and pain in children undergoing chemotherapy: a randomized double-blind clinical trial. double-blind clinical trial.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016061813691N7
Enrollment
60
Registered
2016-08-15
Start date
2016-07-15
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: mucosit. Condition 2: pain. Oral mucositis (ulcerative) Ocular pain

Interventions

Intervention 1: Following chemotherapy with oral ulcers detected in the intervention group adhesive gel containing 1% plant extract twice a day locally in the oral mucosa (on normal mucosa) for five d
Treatment - Drugs
After oral ulcers in the control group than in the placebo following chemotherapy plant extract is an adhesive-free gel topically on healthy mucosa of the mouth twice a day for five days taking part w
Following chemotherapy with oral ulcers detected in the intervention group adhesive gel containing 1% plant extract twice a day locally in the oral mucosa (on normal mucosa) for five days In addition

Sponsors

Vice chancellor for research, Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 14 Years

Inclusion criteria

Inclusion criteria: Entry criteria: full consciousness, admitted to Tabriz Children's Hospital Hematology and Oncology, treatment with chemotherapy drugs cause mucositis (cisplatin, cyclophosphamide and Mtvtrvksayd); at least three years and a maximum of fourteen years, not having the recurrent infectious waste oral, diagnosis (ALL, lymphoma and neuroblastoma). Exclusion criteria: children and parents not wanting to continue working; the death of the child; the child is connected to the ventilator, continuous use painkillers or opiates to relieve pain.As a result the treatment will be compared in the two groups that could be a less costly and less complications used to treat and prevent oral ulcers.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Mucositis. Timepoint: For five days following chemotherapy with oral ulcers. Method of measurement: Czech List View and questionnaire oral ulcers World Health Organization.

Secondary

MeasureTime frame
Pain. Timepoint: For five days following chemotherapy with oral ulcers. Method of measurement: Czech List View and tools Ocher pain.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026