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Combination therapy in vitiligo

The effect of topical piperine combined with narrow band UVB on vitiligo treatment: A clinical trial study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016061527802N2
Enrollment
30
Registered
2017-07-03
Start date
2016-06-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitiligo. Vitiligo

Interventions

Intervention 1: Treatment with NBUVB plus a topical ointment as the placebo. Intervention 2: Treatment with NBUVB plus local application of Piperine solition.
Placebo
Treatment - Drugs
Treatment with NBUVB plus a topical ointment as the placebo
Treatment with NBUVB plus local application of Piperine solition

Sponsors

Vice Chancellor of Research, Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: diagnosis of facial vitiligo Exclusion criteria: history of alopecia areatea; diabetes; Addison's disease; pernicious anemia; Graves disease; Hashimoto’s thyroiditis; systemic lupus erythematosus; history of treatment with NB-UVB in the past two weeks; history of applying topical medications in the past 2 weeks prior to the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

MeasureTime frame
Patients satisfaction. Timepoint: After four months. Method of measurement: Objective score given by the patient on a scale of 0-10.;Side effects of the treatment. Timepoint: Every month. Method of measurement: History taking and physical examination.

Primary

MeasureTime frame
Repigmentation. Timepoint: Every month. Method of measurement: Objective evaluation by two blinded Dermatologists.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAnoosh Shafiee

Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences

anooshshafiee@sbmu.ac.ir+98 21 8836 1563

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026