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Comparison effects of magnesium sulfate and granisetron on prevention of shivering during spinal anesthesia in cesarean section

Clinical trial Comparison effects of magnesium sulfate and granisetron on prevention of shivering during spinal anesthesia in cesarean section

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201606144780N9
Enrollment
80
Registered
2016-08-23
Start date
2015-06-17
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intra and post spinal anesthesia shivering. Hypothermia, not associated with low environmental temperature

Interventions

Intervention 1: Intervention group 1: 30mg/kg Magnesium sulfate diluted and brought to the volume of 50cc syringe infusion pump over 30 minutes we were. Intervention 2: Intervention group 2 : Graniset
Treatment - Drugs
Intervention group 1: 30mg/kg Magnesium sulfate diluted and brought to the volume of 50cc syringe infusion pump over 30 minutes we were
Intervention group 2 : Granisetron a dose of 40mcg/kg in the syringe injected encoded so that neither the researchers nor the patients had knowledge of the contents of the syringe.

Sponsors

Vice Chancellor for Research Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Pregnant women who underwent spinal anesthesia for cesarean section are ASA class I. Exclusion criteria: Patients with ASA class II and above; Sensitivity to study drugs; Thyroid disease; Parkinson; Ischemic heart disease; Reception blood intraoperative; Surgery for more than 120 minutes or less than 30 minutes; History of pethidine; use of pethidine; Hypertension; Renal disease; usage of heart and blood pressure drug.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Shiver. Timepoint: Every 15 minutes to 120 minutes during surgery. Method of measurement: With Crossly and Mahjon five-point scoring system and tympanic thermometer devices.

Secondary

MeasureTime frame
Blood pressure. Timepoint: Evey 15 minutes to 120 minutes during surgery. Method of measurement: Using a non-invasive cuff.;Heart rate. Timepoint: Every 15 minutes to 120 minutes during surgery. Method of measurement: With monitoring device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Ali Alipour

Mashhad University of medical sciences

alipourm@mums.ac.ir+98 51 3801 2612

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026