Mitral valve surgery. Mitral (valve) failure
Conditions
Interventions
Intervention 1: In order to immobilize the heart in the intervention group, hyperkalemic cardioplegic solution with adenosine 2 mM will be used in the intervention group. Intervention 2: In order to i
Sponsors
Rajaee hospital
Eligibility
Sex/Gender
All
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: patients' willingness to participate in research; written informed consent; all of patients with mitral valve disease. Exclusion criteria: patients with aortic valve disease; pulmonary disease; two valves diseases; coronary heart disease; liver disease; kidney disease; lung disease; high blood pressure; diabetes; asthma; heart surgery; cardiac output less than 30%; history of adenosine-sensitivity and all the patients had a previous surgical history.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TNF-a. Timepoint: Before and after the intervention. Method of measurement: Laboratory analysis of blood samples. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic parameters. Timepoint: 1. Basic 2-15 minutes after CPB 3-6 hours after CPB 4-24 hours after CPB. Method of measurement: Heart rhythm ECG, Blood pressure by artelain, CVP transducer dome. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFahimeh Ghasemi
Rajaee Hospital
Outcome results
None listed