Ischemic stroke. Cerebral infarction, unspecified
Conditions
Interventions
Intervention 1: Control group: patients in this group receive routine hospital feeding. Intervention 2: Intervention group 1: patients in this group receive daily 20 gr of protein whey in addition to
Treatment - Other
Control group: patients in this group receive routine hospital feeding.
Intervention group 1: patients in this group receive daily 20 gr of protein whey in addition to routine hospital feeding.
Intervention group 2: patients in this group will consume 1200 mg/day in addition to routine hospital feeding and 1 hour after noon feeding.
Intervention group 3: patients in this group will consume daily dose of 20 gr of protein whey plus 1200 mg of lipoic acid in addition to routine hospital feeding.
Sponsors
Vice chancellaor of research and technology , Tabriz university of medical science
Eligibility
Sex/Gender
All
Age
41 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: age more than 40 yars old; hospitalized with definite diagnosis of acute ischemic stroke; NIHSS<=20; start of tube feeding in 48 hours after admission. Exclusion criteria: vegetative ischemic stroke; TPA injected patients; history of chronic diseases (renal failure needing dialysis at admission time); hepatic cirrhosis and liver diseases; chronic respiratory disease; heart failure; history of cancer; epilepsy and GI bleeding; uncontrolled diabetes; history of myocardial infarction in the past 3 months; enteral feeding less than 10 days; alcohol and opioid consumption.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum albumin. Timepoint: base line and 3 weeks later. Method of measurement: Laboratory test, spectophotometric.;Total antioxidant capacity. Timepoint: before intervention and 3 weeks after intervention. Method of measurement: Laboratory test, ELIZA.;C reactive protein. Timepoint: before intervention and 3 weeks after intervention. Method of measurement: Laboratory test, ELIZA.;?Tnf-a. Timepoint: before intervention and 3 weeks after intervention. Method of measurement: Laboratory test, ELIZA.;IL-6. Timepoint: before intervention and 3 weeks after intervention. Method of measurement: Laboratory test, ELIZA. | — |
Secondary
| Measure | Time frame |
|---|---|
| NIHSS. Timepoint: before intervention, 3 weeks after intervention. Method of measurement: observation with physical examination.;MRS. Timepoint: before intervention, 3 weeks after intervention and 3 months after intervention. Method of measurement: observation with physical examination.;Quality of life. Timepoint: 3 weeks after intervention. Method of measurement: SF-36 Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Mohammad khalili
Tabriz University of Medical Sciences
Outcome results
None listed