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Effects of Resistance Exercise Training on Postmenopausal Women with Knee Osteoarthritis

Effects of Resistance Exercise Training on IL-6,TNF-a, hsCRP, GH, IGF-1, Estrogen, Adiponectin, Resistin, Insulin resistance and Balance in Postmenopausal Women with Knee Osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016061428406N2
Enrollment
21
Registered
2016-07-04
Start date
2013-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis. Arthrosis of knee

Interventions

Intervention 1: Experimental group: The subjects performed resistance exercise training 8 to 12 times with an intensity of 60 – 80% of one of their maximum repetition for a period of 12 weeks, three s
Lifestyle
Experimental group: The subjects performed resistance exercise training 8 to 12 times with an intensity of 60 – 80% of one of their maximum repetition for a period of 12 weeks, three sessions a week.

Sponsors

Shahrekord University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: knee arthritis; pain on > 50 % of days in the month in one or both knees; difficulty with activities of daily living due to knee pain; X-ray documenting knee OA within 1 year prior to study entry; 15 lbs to 50 lbs overweight. Exclusion criteria: significant cardiac, pulmonary, renal, or hepatic disease; major psychiatric diseases; ACR functional class IV; structured exercise more than once per week for 20 minutes or longer during the 3 months prior to study entry; anticipates moving from the area within 18 months of study entry; anticipates undergoing knee surgery within 1 year of study entry; weight loss of more than 5 kg (11 lbs) in 3 months prior to study entry; anorexiant or other medications known to affect metabolism; current or planned pregnancy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
TNF-a. Timepoint: Before and after 12 weeks of resistance exercise training. Method of measurement: Elisa Kit.;IL-6. Timepoint: Before and after 12 weeks of resistance exercise training. Method of measurement: Elisa Kit.;Resistin. Timepoint: Before and after 12 weeks of resistance exercise training. Method of measurement: Elisa Kit.;HsCRP. Timepoint: Before and after 12 weeks of resistance exercise training. Method of measurement: Elisa Kit.;Adiponectin. Timepoint: Before and after 12 weeks of resistance exercise training. Method of measurement: Elisa Kit.;Insulin Resistance. Timepoint: Before and after 12 weeks of resistance exercise training. Method of measurement: Elisa Kit.;GH. Timepoint: Before and after 12 weeks of resistance exercise training. Method of measurement: Elisa Kit.;IGF-1. Timepoint: Before and after 12 weeks of resistance exercise training. Method of measurement: Elisa Kit.;Estrogen. Timepoint: Before and after 12 weeks of resistance exercise training. Method of measurement: Elisa Kit.;Balance. Timepoint: Before and after 12 weeks of resistance exercise training. Method of measurement: Standard test for balance.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAkbar Azamian Jazi

Shahrekord University

azamianakbar@gmail.com+98 38 1442 4411

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026