Transplanted kidney function. Chronic kidney disease, stage 5
Conditions
Interventions
Intervention 1: Intervention group: Capsule of Azithromycin 1 g, 24 hours before nephrectomy, Made in Iran. Intervention 2: Control group: Capsule of placebo 1 g, 24 hours before nephrectomy, Made in
Treatment - Drugs
Placebo
Intervention group: Capsule of Azithromycin 1 g, 24 hours before nephrectomy, Made in Iran
Control group: Capsule of placebo 1 g, 24 hours before nephrectomy, Made in Iran
Sponsors
Urology Research Centre, Guilan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: Alive or cadaveric donor; Sign the inform consent by donor or Family of cadaver Exclusion criteria: Allergic components or allergic to various brands of Azithromycin; Severe medical disease like heart, liver, renal, hematological; respiratory, cardiovascular, psychiatric or other problem pre transplantation in donor; Consumption of other medication including Macrolides family; Involvement in additional clinical trials at the same time
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| GFR. Timepoint: 1 day, 2 days, 4 days, 30 days and 90 days after transplantation. Method of measurement: Cockcroft-Gault Equation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Complication. Timepoint: 1 day, 2 days, 4 days, 30 days and 90 days after transplantation. Method of measurement: Registration of physical examination, medical history and paraclinical findings.;Pain score in donors. Timepoint: 1 day, 2 days and 4 days after transplantation. Method of measurement: Visual Analog Scale (VAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mojtaba Teimoori
Urology Research Center
Outcome results
None listed