Fracture of shaft of femur. Fracture of shaft of femur
Conditions
Interventions
Control group: Just like the tranexamic acid group except that instead of tranexamic acid, normal saline will be used
Intervention 1: Tranexamic acid group: Injection of a bolus of 10 mg/kg of tranexamic acid before the surgery and then venous injection of 1 mg/kg/h of that till the end of the surgery. Intervention
Prevention
Tranexamic acid group: Injection of a bolus of 10 mg/kg of tranexamic acid before the surgery and then venous injection of 1 mg/kg/h of that till the end of the surgery
Sponsors
Vice chancellor for research, Zahedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 139 Years
Inclusion criteria
Inclusion criteria: Inclusion criterion: patients above the age of 18 who are going to undergo femoral shaft fracture surgery in Khatam al Anbiya Hospital in 2016-2017 Exclusion criteria: allergy to tranexamic acid; coagulant use 5 days before the surgery; hematuria and platelet count of less than 150000
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of blood loss during femoral shaft fracture surgery. Timepoint: During the surgery, up to 48 hours after the surgery. Method of measurement: By counting the bloody guazes and measuring the suctioned blood during the surgery and also the drainage up to 48 hours after surgery. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMostafa Hosseini Mofrad
Zahedan University of Medical Sciences
Outcome results
None listed