Condition 1: Toxic effect of organic solvents. Condition 2: Toxic effect of metals. Condition 3: Toxic effect of metals. Homologues of benzene Lead and its compounds Cadmium and its compounds
Conditions
Interventions
Intervention 1: The intervention group consists of 20 workers exposed to organic solvents in the printing industry and 20 workers exposed to heavy metals in the tile industry who received capsules 60
Placebo
The intervention group consists of 20 workers exposed to organic solvents in the printing industry and 20 workers exposed to heavy metals in the tile industry who received capsules 60 mg oral COQ10 t
The control group consists of 20 workers exposed to organic solvents in the printing industry and 20 workers exposed to heavy metals in the tile industry who received capsules 60 mg oral placebo twice
Sponsors
Zahedan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: Having at least one year of experience in the production line; giving consent to participate in the study Exclusion criteria: History of chronic diseases of the thyroid, liver, kidney, diabetes, cardiovascular disease, cancer and high blood pressure; use of antioxidant supplements by person; Having Positive test G6PDH
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Malondialdehyde. Timepoint: Before the intervention, two months after the intervention. Method of measurement: Measurement of blood plasma levels of malondialdehyde in terms of nmol per ml.;Total antioxidant capacity. Timepoint: total antioxidant capacity. Method of measurement: Measurement of antioxidant capacity in blood plasma in terms of micromoles per liter.;Superoxide dismutase activity. Timepoint: Before the intervention, two months after the intervention. Method of measurement: Measurment of the level of erythrocyte superoxide dismutase activity in terms of unit per gram of hemoglobin.;Glutathione peroxidase activity. Timepoint: Before the intervention, two months after the intervention. Method of measurement: Measurment of the level of erythrocyte glutathione peroxidase activity in terms of unit per gram of hemoglobin.;Catalase activity. Timepoint: Before the intervention, two months after the intervention. Method of measurement: Measurment of the level of erythrocyte catalase activity in terms of unit per gram of hemoglobin. | — |
Secondary
| Measure | Time frame |
|---|---|
| Headache. Timepoint: Before the intervention and at the end of intervention. Method of measurement: According to Commenting person.;Nausea. Timepoint: Before the intervention and at the end of intervention. Method of measurement: According to Commenting person. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Hormozi
Zahedan University of Medical Sciences
Outcome results
None listed