Preterm infants. Digestive system disorders of fetus and newborn
Conditions
Interventions
Intervention 1: Intervention group 1: this group will received 5 drops of milk fortified with 108 Colony Forming Unit per ml (cfu/ml) of Lactobacillus plantarum and 0.8 grams per dL fructooligosacch
Treatment - Drugs
Intervention group 1: this group will received 5 drops of milk fortified with 108 Colony Forming Unit per ml (cfu/ml) of Lactobacillus plantarum and 0.8 grams per dL fructooligosaccharides twice a d
Intervention 2: this group will received 5 drops of milk fortified with 108 cfu/ml of Lactobacillus plantarum twice a day for two weeks
Intervention 3: this group will received 5 drops of milk fortified with 0.8 grams per dL fructooligosaccharides twice a day for two weeks
Control group: this group will received regular milk twice a day for 2 weeks.
Sponsors
Vice chancellor for research, Alborz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 14 Days
Inclusion criteria
Inclusion criteria: Inclusion criteria: Infants weighing less than 2500 g or 37 week; all premature infants hospitalized in Kamali Hospital of Karaj Exclusion criteria: in the case of clinical symptoms of Sepsis (including severe lethargy, inability to feed, frequent vomiting, impaired consciousness, seizures, severe abdominal distention, laboratory findings such as positive blood culture and elevated CRP); critically ill patient for any reason.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body Weight. Timepoint: 14 days. Method of measurement: weightening for body weight.;Fecal lactate. Timepoint: 14 days. Method of measurement: GC-MASS.;Fecal calprotectin. Timepoint: 14 days. Method of measurement: ELISA kit.;Fecal acetate. Timepoint: 14 days. Method of measurement: GC-MASS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hospitalization in. Timepoint: day of discharge from hospital. Method of measurement: Counting days. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahboobeh Mehrabani Natanzi
Alborz University of Medical Sciences
Outcome results
None listed