Effect of heparin and clopidogrel on mortality rate in heart surgery

Comparison of the effect of heparin and clopidogrel on hospital and one month later mortality rate in patients undergoing coronary artery bypass graft (CABG) surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016060528285N1

Enrollment

200

Registered

2016-07-01

Start date

2016-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: coronary artery bypass graft. Condition 2: . Unspecified complication of cardiac and vascular prosthetic device, implant and graft Fracture of shaft of femur

Interventions

Intervention 1: Heparin group: receiving the drug as follows: on the day of surgery, 300-400 unit during the surgery and a repeat of half dose one hour and a half later, on the next 3 days, 250-1000 u

Treatment - Drugs

Heparin group: receiving the drug as follows: on the day of surgery, 300-400 unit during the surgery and a repeat of half dose one hour and a half later, on the next 3 days, 250-1000 unit/hour and on

Clopidpgrel group: receiving the drug as 75 mg/kg for 5 days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: All the patients undergoing CABG in Ali ebne Abi Taleb Hospital in 2016-2017 Exclusion criteria: necessity of valve replacement; having AF rhythm; receiving warfarin for another reason

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Mortality rate. Timepoint: In hospital, one month after discharge from hospital. Method of measurement: By asking the patient's family.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdy Sargazifar

Zahedan University of Medical Sciences

mehdysargazifar@zaums.ac.ir+98 54 3223 0896

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026